ACAN

ACAN
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	4MD4
Dynodwyr
Cyfenwau	ACAN, AGC1, AGCAN, CSPG1, CSPGCP, MSK16, SEDK, Aggrecan, SSOAOD
Dynodwyr allanol	OMIM: 155760 HomoloGene: 136177 GeneCards: ACAN
Patrwm RNA pattern
	; ; ; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• extracellular matrix structural constituent; • metal ion binding; • GO:0001948, GO:0016582 protein binding; • hyaluronic acid binding; • carbohydrate binding; • extracellular matrix structural constituent conferring compression resistance;
Cydrannau o'r gell	• GO:0005578 extracellular matrix; • extracellular region; • lysosomal lumen; • Golgi lumen; • basement membrane; • collagen-containing extracellular matrix; • perisynaptic extracellular matrix; • glutamatergic synapse; • GABA-ergic synapse;
Prosesau biolegol	• skeletal system development; • extracellular matrix disassembly; • extracellular matrix organization; • proteolysis; • central nervous system development; • keratan sulfate catabolic process; • keratan sulfate biosynthetic process; • cell adhesion; • cartilage condensation; • chondrocyte development; • heart development; • proteoglycan biosynthetic process; • collagen fibril organization;
	Sources:Amigo / QuickGO
Orthologau
	176
	n/a
	ENSG00000157766
	n/a
	P16112
	n/a
	NM_001135; NM_013227; NM_001369268
	n/a
	NP_001126; NP_037359; NP_001356197
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ACAN yw ACAN a elwir hefyd yn Aggrecan core protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 15, band 15q26.1.^[2]

[1] "Human PubMed Reference:".

[2] ACAN - Cronfa NCBI

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